CBR 5884
CBR-5884
CAS: 681159-27-3
Molecular Formula: C14H12N2O4S2
CBR 5884 - Names and Identifiers
CBR 5884 - Physico-chemical Properties
| Molecular Formula | C14H12N2O4S2 |
| Molar Mass | 336.39 |
| Density | 1.43±0.1 g/cm3(Predicted) |
| Boling Point | 378.1±42.0 °C(Predicted) |
| Solubility | 10 mM in DMSO |
| Appearance | paste |
| Color | white to beige |
| pKa | 11.25±0.70(Predicted) |
| Storage Condition | 2-8°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months. |
CBR 5884 - Preparation solution concentration reference
| 1mg | 5mg | 10mg | |
|---|---|---|---|
| 1 mM | 2.973 ml | 14.864 ml | 29.728 ml |
| 5 mM | 0.595 ml | 2.973 ml | 5.946 ml |
| 10 mM | 0.297 ml | 1.486 ml | 2.973 ml |
| 5 mM | 0.059 ml | 0.297 ml | 0.595 ml |
Last Update：2024-01-02 23:10:35
CBR 5884 - Reference Information
| biological activity | CBR-5884 is a selective inhibitor of phosphoglycerate dehydrogenase (PHGDH), the corresponding IC50 value was 33 μm. CBR-5884 inhibits de novo Serine Synthesis in cancer cells and is selectively toxic to cancer cells with homoserine biosynthetic activity. |
| Target | TargetValue PHGDH (Cell-free assay) 33 μm |
| Target | Value |
| PHGDH (Cell-free assay) | 33 μM |
Last Update：2024-04-09 20:48:19
Supplier List
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Product Name: CBR-5884 Visit Supplier Webpage Request for quotationCAS: 681159-27-3
Tel: 18301782025
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Spot supply
Product Name: CBR-5884 Visit Supplier Webpage Request for quotationCAS: 681159-27-3
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409
Wechat: 18301782025
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